PuriLinX® is a benchtop chromatography system suitable for laboratory scale. It has high basic configuration, accurate and stable flow, high pressure resistance, and sensitivity in detection. The software has complete functions to meet the needs of various chromatography process development. Integrating functions such as instrument control, method editing, data analysis, standard curve, report generation, user permissions management, and audit trail, the software complies with relevant FDA/GLP/GMP regulations.
High configuration (dual-pump and double-bubble sensor, dual-pump back pressure valve, column valve, multi-channel loading valve, multi-channel outlet valve, and DAD ultraviolet detector), to meet diverse needs of chromatography process development
Classic duplex plunger parallel pump with reliable control and mechanical components, providing high accuracy and long-term stability
Detector adopting modular design, with independent coupled light source and highly sensitive polychromator spectral analysis system
External flow path design to avoid intersection with circuits, preventing accidental liquid leakage from damaging electrical components and prolonging the service life of the equipment
Humanized design of the instrument shell, elegant appearance, easy to operate and maintain
Linkage control of instrument and software, supporting wireless connection; user-friendly system software in line with the habits of laboratory personnel, supporting custom editing
Pump system
With a classic duplex plunger parallel pump and reliable control and mechanical components, the system runs stably for a long time and provides accurate flow output.
Small dead volume of the pulse damper
Advanced cam technology and a double piston mechanism, providing virtually pulse-free fluid delivery
Specially designed for chromatographic separation and liquid phase analysis, featuring a large flow range, high accuracy, and small pulse
Standard fluid path materials: stainless steel and PEEK
DAD detector
DAD400 is an ultraviolet diode array detector specially developed for fields such as chromatography, environmental protection, and online monitoring.
The detector adopts a modular and separate design, has an independent coupled light source and a highly sensitive polychromator spectral analysis system, uses comprehensive methods to suppress stray light and circuit noise, and has a good dynamic range and excellent resolution.
Czerny-Turner polychromator spectral analysis system
The optical fiber is used to connect the flow cell, effectively isolating the heat source and facilitating maintenance
Multiple wavelengths can be set simultaneously
No mechanical motion parts, excellent stability
Rich output interfaces, easy to adapt
Bubble sensor
The ultrasonic bubble sensor is a standardized and easy-to-use sensor specially developed to achieve online fluid bubble monitoring in laboratories and processes, requiring no ultrasonic couplants.
Requiring no couplants, non-contact detection
No damage to the sample
Flexible and easy to use, dual-color LED indicator light
Collection rack
The new generation of general component collector can be used alone or in combination with a protein purification system.
Collection type: 96-well plate, 13 mm test tube rack, 16 mm test tube rack, 30 mm test tube rack
The test tube rack tray is applicable to all collection types, with no need to be changed
Matching other domestic and foreign generators, the instrument provides a wealth of external interfaces and a separate touch-screen control system
No. | Interface description | No. | Interface description |
1 | Power interface | 5 | Trigger interface (electrical level/short circuit/relay) |
2 | Network cable interface | 6 | Analog input interface |
3 | RJ12 interface | 7 | Solenoid valve data cable interface |
4 | COM serial port (232/485) |
Mixer
Mixing is performed by a dynamic, electromagnetically driven mixer, and the volume of the mixing pool is 2 mL
pH detector (including temperature compensation)
Detection range: pH: 0 – 14; detection precision: 0.1 pH
Conductivity detector (including temperature compensation)
Detection range: 0 –999.999 mS/cm; detection precision: ±2%
Smart Power is a specially developed intelligent and easy-to-use control system software that adopts a separate component design to enable customers to quickly master the skills of using the software.
Result analysis:
The software provides comprehensive analysis functions such as spectrum comparison, peak analysis, column efficiency analysis, and result export, and provides effective data analysis support for small-scale screening and process scale-up studies.
Data storage:
Automatic backup to ensure data security
Method editing:
Text editing to meet more complicated requirements for method editing
Configuration option | Name | Technical parameters | |
Standard configuration | PuriLinX infusion pump | PuriLinX® 36 | PuriLinX® 100 |
Dual-pump system flow rate range: 0.01 – 36 mL/min; pressure resistance range: 0 – 34.5 MPa (5000 psi); flow accuracy: ±1.5% | Dual-pump system, flow rate range: 0.01 – 100 mL/min; pressure resistance range: 0 – 10.3 MPa (1500 psi); flow accuracy: ±1.5% | ||
Flow rate repeatability: RSD ≤ 0.5% Gradient type: linear, isocratic, stagewise gradient, gradient ratio can be modified online | |||
Inlet channel | 4 channels: A1, A2, B1, B2 | ||
Bubble sensor | Ultrasonic detection, two sensors (A/B), standard configuration | ||
Mixer | Electromagnetically driven mixer | ||
Injection valve | High-pressure 6-way valve, supporting load, inject, and waste modes | ||
Column valve | High-pressure 6-way valve, supporting upflow, downflow, and bypass modes | ||
DAD detector | DAD400 has variable four-wavelength with a detection range of 190-400 nm, enables direct reading of full spectrum, and can detect four arbitrary wavelengths simultaneously Wavelength range: 190 – 400 nm Channel: quadruple channel Wavelength accuracy: 1 nm | ||
PH online sensor | Range: 0 – 14; accuracy: ±0.1; temperature compensation: yes | ||
Conductivity online sensor | Range: 0 –999.99 ms/cm; accuracy: ±2%; temperature compensation: yes | ||
Pressure sensor | Pre-column pressure monitoring | ||
Online filter | 20 μm PP filter disc | ||
Component collector module | Collection type: 1-way liquid waste, 1-way collection by collector Placement of: 4 96-well plates; 2 13-mm test tube racks; 2 16-mm test tube racks; 2 30-mm test tube racks | ||
Accessory package | Including pipeline, connector, maintenance tool, instructions for use, and dongle, etc. | ||
Control system | Control system (including computer, keyboard, mouse, English and Chinese operating software) can achieve 24-h uninterrupted operation | ||
Configuration selection | Buffer inlet valve | 9-channel: pump A: A1-1 to A1-6, A2; pump B: B1, B2 | |
Outlet valve | 6-channel: 1-way liquid waste, 4-way bulk collection, 1-way collection by collector | ||
Sample pump | SP36D: flow rate range 0.01-36mL/min, pressure resistance range 0-34.5MPa, flow rate accuracy ±1.5%. | ||
SP100D: flow rate range 0.01-100mL/min, pressure resistance range 0-10.3MPa, flow rate accuracy ±1.5%. | |||
Four column position valve | Can connect four chromatography columns at the same time, support upflow, downflow, bypass |
BLKX3601 | PuriLinX 36D | 36 mL dual-pump system, 2 inlets for pump A, 2 inlets for pump B, 1 automatic collection outlet, 1 waste liquid outlet, 1 bulk collection outlet | 4 inlets, 3 outlets |
BLKX3602 | PuriLinX 36S | 36 mL dual-pump system, 6+1 inlets for pump A, 2 inlets for pump B, 1 automatic collection outlet, 1 waste liquid outlet, 1 bulk collection outlet | 9 inlets, 3 outlets |
BLKX3603 | PuriLinX 36M | 36 mL dual-pump system, 2 inlets for pump A, 2 inlets for pump B, 1 automatic collection outlet, 1 waste liquid outlet, 4 bulk collection outlets | 4 inlets, 6 outlets |
BLKX3604 | PuriLinX 36L | 36 mL dual-pump system, 6+1 inlets for pump A, 2 inlets for pump B, 1 automatic collection outlet, 1 waste liquid outlet, 4 bulk collection outlets | 9 inlets, 6 outlets |
BLKX1001 | PuriLinX 100D | 100 mL dual-pump system, 2 inlets for pump A, 2 inlets for pump B, 1 automatic collection outlet, 1 waste liquid outlet, 1 bulk collection outlet | 4 inlets, 3 outlets |
BLKX1002 | PuriLinX 100S | 100 mL dual-pump system, 6+1 inlets for pump A, 2 inlets for pump B, 1 automatic collection outlet, 1 waste liquid outlet, 1 bulk collection outlet | 9 inlets, 3 outlets |
BLKX1003 | PuriLinX 100M | 100 mL dual-pump system, 2 inlets for pump A, 2 inlets for pump B, 1 automatic collection outlet, 1 waste liquid outlet, 4 bulk collection outlets | 4 inlets, 6 outlets |
BLKX1004 | PuriLinX 100L | 100 mL dual-pump system, 6+1 inlets for pump A, 2 inlets for pump B, 1 automatic collection outlet, 1 waste liquid outlet, 4 bulk collection outlets | 9 inlets, 6 outlets |
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