The semi-automatic TFF system adopts a modular design and is available in benchtop and floor-standing models. It is equipped with filter holders of different specifications. According to process requirements, the circulation pump can be flexibly configured with a rotor pump or a diaphragm pump.
The system is designed to be compact and practical. With automatic feedback and adjustment of the flow rate and pressure, the automatic control of TMP and Delta P is available, thereby realizing the automatic operations of concentration, diafiltration, desalting, and dealcoholizing of biological products such as antibodies, vaccines, blood products, and gene therapy drugs.
Due to its automatic operation, cost-effectiveness, and compliance with regulations related to data integrity, the system is an ideal choice for filtration systems in pilot-scale manufacturing, medical product manufacturing for clinical use, and the GMP manufacturing phase for some products, especially for polyvalent pneumococcal vaccines, blood products, gene therapy medicines, and cell therapy drugs.
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