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FiltraLinX® Benchtop Semi-automatic TFF System

FiltraLinX® semi-automatic benchtop TFF system adopts a modular design and can be equipped with different specifica-tions of hollow fiber filters to achieve a filtration area of 0.017-5.1 m2.


The hollow fiber TFF semi-automatic system is designed compact and practical, with a small circulation volume, making it suitable for high-concentration ap- plications.


Depending on the process requirements, a low-shear four element diaphragm pump is selected as the circulating pump, and the semi-automatic hollow fiber TFF system is equipped with a touchscreen speed control panel. The TFF semi-automatic hollow fiber system allows for adjusting flow rate on the panel to control tangen-tial flow, and achieving the optimization of TMP point by adjusting the pressure at the reflux and permeation ends, thus real-izing the concentration, diafiltration, desalination, dealcoholization and other operations for bioproducts such as antibodies, vaccines, blood products, and gene therapy drugs.


With high cost-effectiveness and compliance with relevant regulations, the FiltraLinX® semi-automatic benchtop TFF system is an ideal choice for lab-scale R&D, pi-lot-scale production, as well as GMP production of specific varieties.


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Video Features Technical Parameters Supporting Documents Ordering Information Contact us

Video of Semi-Automatic Benchtop TFF System

Features of FiltraLinX® Benchtop Hollow Fiber TFF Semi-Automatic System

  • Hollow fiber filtration family with consistency and linearity, which can ensure the seamless transition of process scale-up or  scale-down;

  • Various specifications available: 0.017-1.1 m2 hollow fiber filters;

  • Equipped with the electric proportional control valve, pressure sensor, etc., realizing automatic adjustment of TMP;

  • Fully functional with data recording, audit trial, permission management, etc.;

  • Flexible connections, compatible with single-use storage and mixing bags used for the collection of product concentrations;

  • Equipped with filtration tank, used for the temporary storage of the product concentration, defiltration, harvests and  clarifications;

  • Capable of automatically performing both the water flux test and the filter test;

  • With high compatibility, compatible with hollow fiber filters and cassettes membrane;

  • The frame is made of wear-resistant 304 stainless steel, and the part in contact with the product is made of 316L stainless  steel;

  • Polishing for the outer surface Ra ≤ 1.2 μm, polishing for the part in contact with the product Ra ≤ 0.4 μm;

  • The part in direct contact with the feed liquid is made of sanitary grade materials, such as 316L stainless steel, EPDM/PTFE/ TPE, etc. Certifications of the materials are available upon request;

  • System pipeline withstands pressure up to 6 bar;

  • Full set of accessories including hollow fiber bracket, allowing for use upon arrival directly.


Technical Parameters of FiltraLinX® Benchtop Semi-Automatic Hollow Fiber TFF System

ModelTS-CMV-S01TS-CMV-S03TS-CMV-S20
Pump flow rate60 L/h180 L/h1200 L/h
Compatible membrane area0.017-0.035 m20.017-0.2 m20.1-1.1 m2
Pipeline i.d. (mm)7.75 mm9.4 mm15.75 mm
Control leveSemi-automatic control
Operating pressureMaximum 5 bar
System pressure resistanceMaximum 6 bar
Operating temperature4-60℃
Bracket baseplateSS 304
Pipeline fittingsSS 304
Diaphragm pumpSS 316L
Electric proportional control valveSS 316L
Pressure sensorSS 316L
Surface finishPolishing for the surface Ra ≤ 1.2 µm, polishing for the part in contact with the product Ra ≤ 0.4 µm
Sanitary connectionTC chuck

* Customization available upon request. For details, please consult the local sales or call the hotline 4000589000.


Supporting Documents of FiltraLinX® Benchtop TFF Semi-Automatic Hollow Fiber System

  • Quality certificates

  • GA drawings

  • IQ/OQ validation files (optional)

  • List of spare parts

  • Certificates of the equipment pressure instruments

  • System operating manuals

  • Material certification: Certification of the SS 316L stainless steel material in contact with the feed liquid

  • Certification of the surface finish


Ordering Information of FiltraLinX® Semi-Automatic Benchtop TFF System

Product descriptionCat. No.Control systemCirculation systemFiltration tankCollection tank
Semi-automatic hollow fiber
TFF system, applicable for
0.017-0.035 m2		TS-CMV-S01√√√√
Semi-automatic hollow fiber
TFF system, applicable for
0.017-0.035 m2		TS-CMV-S03√√√√
Semi-automatic hollow fiber
TFF system, applicable for
0.1-1.1 m2
TS-CMV-S20√√√√


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