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FiltraLinX® Benchtop Manual Hollow Fiber TFF System

FiltraLinX® Benchtop Manual Hollow Fiber TFF system adopts a modular design and can be equipped with different specifications of hollow fiber filters to achieve a filtration area of 0.017-5.1 m2 .


The manual hollow fiber TFF system is designed compact and practical, with a small circulation volume, making it suitable for high-concentration applications.


Depending on the process requirements, a low-shear four element diaphragm pump is selected as the circulating pump, and the manual benchtop TFF system is equipped with a touchscreen speed control panel. The hollow fiber TFF manual system allows for adjusting flow rate on the panel to control tangential flow, and achieving the optimization of TMP point by adjusting the pressure at the reflux and permeation ends, thus realizing the concentration, diafiltration, desalination, dealcoholization and other operations for bioproducts such as antibodies, vaccines, blood products, and gene therapy drugs.


With high cost-effectiveness and compliance with relevant regulations, the TFF manual hollow fiber system is an ideal choice for lab-scale R&D, pilot-scale production, as well as GMP production of specific varieties.



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Features Technical Parameters Supporting Documents Ordering Information Contact us

Features of FiltraLinX® Manual Benchtop Hollow Fiber TFF System

  • Hollow fiber filtration family with consistency and linearity, which can ensure the seamless transition of process scale-up or scale-down;

  • Available in various specifications: 0.017-5.1 m2 hollow fiber filters;

  • Flexible connections, compatible with single-use storage and mixing bags used for the collection of product concentrations;

  • Equipped with manual valves, circulating pumps, pressure gauges and other components to achieve manual adjustment of  reflux and permeate end pressure;

  • Can be equipped with peristaltic pumps for feeding;

  • Can be equipped with filtration tank used for product concentration, defiltration and temporary storage of harvests and clarifications;

  • Allowing for a water flux test, and a membrane integrity testing port is reserved;

  • Capable of using flat sheet membrane;

  • Wear-resistant 304 stainless steel for racks and 316L stainless steel for product contact parts;

  • External surface finish Ra ≤ 1.2 μm, the finish of product contact parts Ra ≤ 0.4 μm;

  • The parts in direct contact with the feed liquid are made of sanitary-grade materials, such as 316L stainless steel, EPDM/ PTFE/TPE. Material certificates are available;

  • System pipeline withstands pressure up to 6 bar;

  • Optional pressure gauges with qualified measurement and suitable ranges;

  • The system is equipped with fixtures and complete accessories, which can be used directly upon arrival.


Technical Parameters of FiltraLinX® Benchtop Hollow Fiber TFF Manual System

Equipment modelTS-HMV-D01TS-HMV-Q03TS-HMV-Q20TS-HMV-Q40
Pump flow rate60 L/h180 L/h1200 L/h2500 L/h
Compatible membrane area0.017-0.035 m20.017-0.2 m20.1-1.1 m20.53-5.1 m2
Pipeline i.d. (mm)7.75 mm9.4 mm15.75 mm22.1 mm
Control levelManual
Operating pressureMax. 5 bar
System pressure resistanceMax. 6 bar
Operating temperature4-60°C
Bracket baseplateSS 304
Pipeline fittingsSS 316L
Diaphragm pumpSS 316L
Manual diaphragm valveSS 316L
Diaphragm pressure gaugeSS 316L
Surface finishSurface finish Ra ≤ 1.2 μm, the finish of product contact parts Ra ≤ 0.4 μm
Sanitary connectionTC chuck

* Customization available upon request. For details, please consult your local sales representative or call our hotline at 4000589000.


Supporting Documents of FiltraLinX® Benchtop TFF Manual Hollow Fiber System

  • Quality certificates

  • GA drawings

  • IQ/OQ validation documentation (optional)

  • List of spare parts

  • Certificates of the equipment pressure instruments

  • System operating manuals

  • Material certificate: SS 316L stainless steel in contact with the feed liquid

  • Certification of the surface finish


Ordering Information of FiltraLinX® Benchtop Manual Hollow Fiber TFF System

Product descriptionCat. NoPower pumpFeeding pumpValvePressure gauge
Manual Hollow Fiber TFF System,suitable for 0.017-0.035 m2TS-HMV-D01√Optional√√
Manual Hollow Fiber TFF System,suitable for 0.017-0.2 m2TS-HMV-Q03√Optional√√
Manual Hollow Fiber TFF System,

suitable for

0.1-1.1 m2

TS-

HMV-

Q20

√Optional√√
Manual Hollow Fiber TFF System,

suitable for

0.53-5.1 m2

TS-HMV-Q40√Optional√√


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