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FiltraLinX® Benchtop Manual Cassette TFF System

FiltraLinX® benchtop manual cassette TFF system adopts a modular design and can be equipped with cassettes of different specifications, to meet filtration area requirements of 0.1-2.5 m2.

This system is designed to be compact and practical, with a small circulation volume, making it suitable for high-concentration applications.

According to the process, a low-shear four-element diaphragm pump is selected as the circulating pump, equipped with a touch-control speed panel. The system allows for adjusting flow rate on the panel to control the tangential flow, and adjusting the pressure at the retentate and permeate ends to achieve the TMP point optimization, thus realizing concentration, diafiltra-tion, desalting, dealcoholization and other operations of bioproducts such as antibodies, vaccines, blood products and gene therapy drugs.

With the characteristics of cost-effectiveness and compliance with relevant regulations, the system is an ideal choice for labo-ratory research, lab-scale and pilot-scale production and GMP production stages of some varieties.


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Features of FiltraLinX® Benchtop Manual Cassette TFF System

  • Cassette filtration system with consistency and linearity, ensuring seamless process scale-up or scale-down;

  • Available in various specifications: 0.1-2.5 m2 cassettes;

  • Equipped with manual valves, circulating pumps, pressure gauges and other components to achieve manual adjustment of retentate and permeate ends pressure;

  • Flexible connections, compatible with single-use storage and mixing bags used for the collection of product concentrations;

  • Capable of using hollow fiber filters;

  • Can be equipped with peristaltic pumps for feeding;

  • Can be equipped with filtration tank used for product concentration, diafiltration and temporary storage of harvests and clarifications;

  • Allowing for a water flux test, and a membrane integrity testing port is reserved;

  • 304 stainless steel for frame, and 316L stainless steel for the part in contact with product;

  • Outer surface polished Ra ≤ 1.2 μm, product contact parts polished Ra ≤ 0.4 μm;

  • The parts in direct contact with the feed liquid are made of sanitary-grade materials, such as 316L stainless steel, EPDM/

  • PTFE/TPE, etc. Material certifications are available;

  • System pipeline withstands pressure up to 6 bar;

  • Optional pressure gauges with qualified measurement and suitable ranges;

  • The system is equipped with holders and complete accessories, which can be used directly upon arrival.


Specifications of FiltraLinX® Benchtop Manual Cassette TFF System

Technical Parameters

Model

TS-CMV-Q03

TS-CMV-Q20

Pump flow rate

180 L/h

1200 L/h

Compatible membrane area

0.1-0.5 m2

0.5-2.5 m2

Pipeline i.d. (mm)

7.75 mm

15.75 mm

Control level

Manual control

Operating pressure

Max. 5 bar

System pressure resistance

Max. 6 bar

Operating temperature

4-60°C

Bracket baseplate

SS 304

Pipeline fittings

SS 316L

Diaphragm pump

SS 316L

Manual diaphragm valve

SS 316L

Diaphragm pressure gauge

SS 316L

Surface finish

Surface polished Ra ≤ 1.2 µm, parts in contact with the product polished Ra ≤ 0.4 µm

Sanitary connection

TC chuck

* Customization available upon request. For details, please consult the local sales or call the hotline 4000589000.


Ordering Information

Product description

Cat. No.

Power pump

Feeding pump

Valve

Pressure gauge

Manual cassette TFF, suitable for 0.1-0.5 m2


TS-CMV-Q03



Optional



Manual cassette TFF, suitable for 0.5-2.5 m2


TS-CMV-Q20



Optional



* For other accessories, please contact your local sales representative and technician for advice.


Supporting Documents of FiltraLinX® Benchtop Manual Cassette TFF System

  • Quality certificates

  • GA drawings

  • IQ/OQ validation documentation (optional)

  • List of spare parts

  • Certificates of the equipment pressure instruments

  • System operating manuals

  • Material certification: SS 316L stainless steel in contact with the feed liquid

  • Certification of the surface finish


Applications of FiltraLinX® Benchtop Manual Cassette TFF System

applications



Membrane Cassettes of FiltraLinX® Benchtop Manual Cassette TFF System

FiltraLinX® Benchtop Manual Cassette TFF System -- Membrane Cassettes


membrane cassettes

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