Downstream Bioprocessing, Types Of Protein Chromatography Resins

In the downstream separation and purification process of biopharmaceuticals, chromatography is one of the indispensable separation methods. BioLink provides customers with 5 different chromatography solutions, including gel filtration chromatography, ion exchange chromatography, affinity chromatography, hydrophobic chromatography and multimodal chromatography. In addition, BioLink also produces chromatography columns and prepacked columns from laboratory to industrial grade. We focus on providing customers with high-quality products, professional solutions and comprehensive after-sales services.

Types of Protein Chromatography

Chromatography Column

A variety of chromatographic empty column, pre-packed column and column used for laboratory and mass production scale.

Chrom-LinX^® Lab-scale Empty Chromatography Column

Chrom-LinX^® Manual Compression Chromatography Column

Chrom-LinX^® Automated Chromatography Column

PuriLinX^® Benchtop Chromatography System

VERDOT Ips² InPlace™ Process-scale Chromatography Column

Prepacked Column

Prepacked columns are ready-to-use chromatography columns with the chromatography resin pre-filled.

ChromaX^® Geldex^® Prepacked Column

Chrom-Trap^® & Chrom-Screen™ Prepacked Column

ChromaX^® A20 Affinity Chromatography Column

Size Exclusion Chromatography Resin

A chromatographic mode for separation based on molecular weight, widely used in downstream separation and purification of bioprocesses.

Chromstar^® FF Resin for Size Exclusion Chromatography

Chromstar^® CL Resin for Size Exclusion Chromatography

Chromstar^® B Resin for Size Exclusion Chromatography

Geldex^® PG Resin for Size Exclusion Chromatography

Puredex^® G Resin for Size Exclusion Chromatography

Puredex^® LH-20 Resin for Size Exclusion Chromatography

Ion Exchange Chromatography Resin

A chromatographic mode in which separation is based on the difference in charge between target products and impurities.

Maxtar^® Resins for Ion Exchange Chromatography

Maxtar^® HR Resins for Ion Exchange Chromatography

MaXtar^® HR XL Resins for Ion Exchange Chromatography

Chromstar^® BB Resins for Ion Exchange Chromatography

Chromstar^® FF Resins for Ion Exchange Chromatography

Chromstar^® HP Resins for Ion Exchange Chromatography

Chromstar^® XL Resins for Ion Exchange Chromatography

Puredex^® Resins for Ion Exchange Chromatography

Affinity Chromatography Resin

Affinity chromatography is a selective chromatography mode that captures target molecules from complex systems based on highly specific biological interactions between two molecules.

MaXtar^® ARPA Affinity Chromatography Resins

MaXtar^® rProtein A Affinity Chromatography Resins

MaXtar^® Protein G Affinity Chromatography Resins

rProtein A Chromstar^® FF Affinity Chromatography Resins

Protein G Chromstar^® 4FF Affinity Chromatography Resins

Protein G Chromstar^® HP Affinity Chromatography Resins

Ni Chromstar^® Affinity Chromatography Resins

IMAC Chromstar^® Affinity Chromatography Resins

MaXtar^® Chelating Affinity Chromatography Resins

Chelating Chromstar^® FF Affinity Chromatography Resins

Glutathione Chromstar^® Affinity Chromatography Resins

MaXtar^® PlasmidCap HR Affinity Chromatography Resins

PlasmidCap Chromstar^® HP Affinity Chromatography Resins

MaXtar^® Heparin Affinity Chromatography Resins

Heparin Chromstar^® Affinity Chromatography Resins

Benzamidine Chromstar^® 4FF Affinity Chromatography Resins

MaXtar^® Blue Affinity Chromatography Resins

Blue Chromstar^® Affinity Chromatography Resins

NHS Activated Chromstar^® 4FF Affinity Chromatography Resins

CNBr Activated Chromstar^® Affinity Chromatography Resins

Hydrophobic Interaction Chromatography

A chromatographic mode of purification based on the difference in hydrophobicity between the product of interest and impurities.

MaXtar^® Hydrophobic Chromatography Resins

MaXtar^® HR Hydrophobic Chromatography Resins

Chromstar^® FF Hydrophobic Chromatography Resins

Chromstar^® HP Hydrophobic Chromatography Resins

Multimodal Chromatography

Multimodal chromatography combines the high resolution of ion exchange and the high salt tolerance of hydrophobic chromatography, so that the chromatography process can be loaded under high-salt conditions, with a higher operability space, suitable for Handle complex samples.

MaXtar^® MMC Multimodal Chromatography Resins

Maxtar^® COLL Multimodal Chromatography Resins

Maxtar^® MMA Multimodal Chromatography Resins

Hydroxyapatite BARONHAP^® Type I&II Multimodal Chromatography Resin

Polymer Chromatography

Maxgo^® 15S Polymer Chromatography

BioLink's Protein Chromatography Unique Advantages

BioLink has a strong technical research and development team, and attaches great importance to the innovation and protection of independent intellectual property rights. The innovative research and development of chromatography media is reflected in the innovative green chemical spheroidization process, coupling methods and ligands. BioLink has a four-level document management quality system and comprehensive after-sales service, which can ensure the high quality of products.

The advantages of BioLink's new continuous production process of agarose microspheres include:

No toxic solvents.
Can realize continuous production.
Easy to scale up with no or short wash times.
Low requirements on the place of production, which can reduce the dependence on the place of origin and processing of agarose raw materials.

BioLink's Protein Chromatography Unique Advantages

Importance of Using Chromatography Media

Chromatography media, like size exclusion chromatography media, play a crucial role in the results and efficiency of separations and purifications. In the biopharmaceutical process, the downstream of the production link needs to improve the purity and yield of the product through separation and purification to ensure product quality and stability. Breakthroughs and innovations in downstream separation and purification processes can improve biopharmaceutical production efficiency and reduce production costs. The development of chromatography media and its process plays an important role in bioprocessing.